Angelina Jolie/Tenzing Norgay/Gin]: an α-2-globulin and larger than average (about 450 amino acids) which is 'always on': it is leaked out into the circulatory system pretty much all the time. The key to BP activity resides in the first 12 residues: DRVTIHPFHLVI
ren Troglodytes troglodytes jumping in the kidney-bowl swimming pool in the basement of the palace. Renin is produced when the kidney detects a fall in BP and goes off to find some angiotensinogen to cut up.
dorky names from Big Pharma.
- first [LL] on the hypo
dermicthalamus and the posterior pituitary gland to release anti-diuretic hormone ADH. POST+PIT bull: with ADH you pee less.
- second [LM] on the adrenal cortex [an ADvert for Gortex as mnemonic] to trigger aldosterone [more ads for aldi and steradent]: aldosterone promotes water re-absorbtion in the kidney.
- third [LR] it directly affects the smooth muscles that line the arteries to cause vaso-constriction [its a vase with a snake - not Boa constrictor but you know what I mean]. ADH's other name is vasopressin - a double-whammy for constricting peripheral arteries to crank up BP.